Semaglutide Weight Loss in Miami, FL
Lose weight effectively with semaglutide — the FDA-approved GLP-1 medication behind Ozempic and Wegovy. Provider-supervised weekly injections with personalized dosing at Femme Aesthetics.
5.0 on Google108 reviewsSouth Miami

- Procedure
- Weekly Injection
- Results Visible
- 4 – 8 Weeks
- Program
- Ongoing
- Downtime
- None
What Is Semaglutide?
Semaglutide is an FDA-approved GLP-1 receptor agonist medication used for chronic weight management. It is the active ingredient in both Ozempic (approved for type 2 diabetes management) and Wegovy (approved specifically for weight loss in adults with obesity or overweight with at least one weight-related condition).
Originally developed to treat type 2 diabetes, semaglutide was found to produce significant weight loss in clinical trials, leading to its approval for weight management at higher doses. At Femme Aesthetics in Miami, our medical providers prescribe semaglutide as part of a medically supervised weight loss program that includes personalized dosing, regular monitoring, and lifestyle guidance.
How Semaglutide Works
Semaglutide belongs to a class of medications called GLP-1 receptor agonists. GLP-1 (glucagon-like peptide-1) is a hormone your body naturally produces in the gut after eating. It plays a key role in regulating appetite and blood sugar levels.
Semaglutide mimics this natural GLP-1 hormone, but with a much longer duration of action — which is why it only needs to be injected once per week. It works through several mechanisms:
- Appetite suppression: Semaglutide acts on GLP-1 receptors in the brain’s appetite centers, reducing hunger signals and increasing feelings of fullness (satiety) after meals.
- Delayed gastric emptying: The medication slows how quickly food leaves your stomach, helping you feel satisfied longer after eating.
- Blood sugar regulation: Semaglutide stimulates insulin release and suppresses glucagon secretion in a glucose-dependent manner, improving blood sugar control.
- Reduced cravings: By acting on the brain’s reward centers, semaglutide can reduce food cravings and the drive to overeat.
The combined effect is a natural reduction in caloric intake without the constant hunger and willpower battles that undermine most diets.
Why Choose Semaglutide
Benefits of Semaglutide for Weight Loss
- 01Clinically Proven 15% Weight LossIn the landmark STEP clinical trials, patients treated with semaglutide 2.4 mg lost an average of 15% of their body weight over 68 weeks — significantly more than diet and exercise alone.
- 02Appetite RegulationSemaglutide reduces hunger and cravings by mimicking the GLP-1 satiety hormone, making it easier to maintain a caloric deficit naturally without constant willpower battles.
- 03Blood Sugar SupportSemaglutide improves insulin sensitivity and blood sugar regulation, making it especially beneficial for patients with pre-diabetes, metabolic syndrome, or type 2 diabetes.
- 04Simple Weekly InjectionOne small subcutaneous injection per week is all it takes. We teach you how to self-administer during your first visit so you can manage it comfortably at home.
- 05Medical SupervisionRegular check-ins with our clinical team to monitor your progress, adjust dosing, manage side effects, and ensure your safety throughout the entire program.
- 06Cardiovascular BenefitsBeyond weight loss, semaglutide has demonstrated cardiovascular benefits in clinical studies, including reduced risk of major cardiovascular events in patients with established heart disease.
Your Visit
What to Expect
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Before Treatment
Consultation & Evaluation
Your semaglutide journey begins with a comprehensive initial consultation. Our clinical team will determine whether semaglutide is the right medication for your weight loss goals and health profile.
- Complete health assessment and review of medical history
- Lab work and blood panel to evaluate metabolic health
- BMI evaluation and body composition analysis
- Discussion of your weight loss goals and realistic expectations
- Review of current medications and potential contraindications
- Explanation of semaglutide vs. tirzepatide to determine the best fit
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During Treatment
Dose Escalation & Weekly Injections
Semaglutide treatment follows a structured dose escalation schedule to minimize side effects and optimize results. The typical schedule is:
- Weeks 1–4: 0.25 mg per week (initiation dose)
- Weeks 5–8: 0.5 mg per week
- Weeks 9–12: 1.0 mg per week
- Weeks 13–16: 1.7 mg per week
- Week 17+: 2.4 mg per week (maintenance dose)
During your first visit, we teach you how to self-administer the subcutaneous injection at home. The injection uses a small, thin needle and takes only a few seconds. You can inject in the abdomen, thigh, or upper arm, rotating sites each week.
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After Treatment
Ongoing Monitoring & Results
Regular follow-up appointments ensure your progress is on track and allow our medical providers to adjust your care as needed. Most patients begin seeing noticeable weight loss within 4 to 8 weeks of starting treatment.
- Regular weigh-ins and progress assessments
- Dosage adjustments based on response and tolerance
- Side effect monitoring and management
- Lifestyle and nutritional guidance to complement medication
- Program continues as long as medically appropriate with ongoing clinical guidance
Possible Side Effects
Like all GLP-1 receptor agonists, semaglutide can cause side effects, most of which are gastrointestinal and tend to occur during the dose escalation phase. Common side effects include:
- Nausea — the most frequently reported side effect, usually mild and improving over time
- Vomiting — typically occurs early in treatment and diminishes with continued use
- Diarrhea — usually mild and self-limiting
- Constipation — can be managed with dietary fiber and hydration
- Stomach pain or bloating — common during dose escalation
- Injection site reactions — occasional mild redness or swelling at the injection site
Serious but rare side effects include pancreatitis, gallbladder problems, and thyroid tumors (observed in animal studies; semaglutide carries a boxed warning regarding medullary thyroid carcinoma risk). Semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2.
Our clinical team monitors you closely throughout the program, and the gradual dose escalation schedule is specifically designed to minimize discomfort as your body adjusts to the medication.
Semaglutide vs. Tirzepatide
Both semaglutide and tirzepatide are effective GLP-1 based medications for weight loss, but they work slightly differently:
- Semaglutide (Ozempic/Wegovy) is a GLP-1 receptor agonist that targets one hormone pathway. Clinical trials showed an average of ~15% body weight loss.
- Tirzepatide (Mounjaro/Zepbound) is a dual GIP/GLP-1 receptor agonist that targets two hormone pathways. Clinical trials showed up to ~22.5% body weight loss.
Both are administered as weekly subcutaneous injections and share similar side effect profiles. The best choice depends on your individual health profile, medical history, insurance coverage, and treatment goals. Our medical providers will evaluate your specific needs during your consultation and recommend the medication best suited for you.
Femme Aesthetics offers both semaglutide and tirzepatide as part of our medical weight loss program. We also offer a dedicated tirzepatide program for patients who may benefit from dual-receptor therapy.
Transparent Pricing
What this costs
Semaglutide is priced by the volume dispensed, which tracks the dose you titrate up to over the course of treatment. Every patient starts with a telemedicine or in-person consultation, and your first one is complimentary.
- Semaglutide 2ml–5ml$350–$4,500
Prices vary with how much product a treatment plan calls for and which areas are treated. See the full menu on our pricing page, or book a consultation and we will quote you before anything begins.
See every priceWhat is semaglutide?
Semaglutide is an FDA-approved GLP-1 receptor agonist medication used for chronic weight management. It is the active ingredient in both Ozempic (approved for type 2 diabetes) and Wegovy (approved specifically for weight loss in adults with obesity or overweight with at least one weight-related condition). It works by mimicking the GLP-1 hormone that regulates appetite and blood sugar, helping you feel fuller longer and reducing cravings.
How much weight can I lose with semaglutide?
Clinical trials have shown that patients using semaglutide 2.4 mg for weight loss lost an average of 15% of their body weight over 68 weeks. Individual results vary depending on starting weight, adherence to the program, diet, and activity level. Our medical providers will set realistic expectations during your consultation based on your personal health profile.
What are the side effects of semaglutide?
The most common side effects include nausea, vomiting, diarrhea, constipation, and stomach pain. These gastrointestinal symptoms are typically mild to moderate and tend to diminish as your body adjusts to the medication, especially during the dose escalation phase. Serious but rare side effects include pancreatitis and gallbladder problems. Our clinical team monitors you closely throughout the program to manage any symptoms.
How is semaglutide administered?
Semaglutide is administered as a once-weekly subcutaneous injection, typically in the abdomen, thigh, or upper arm. During your first visit, our clinical team teaches you how to self-administer the injection safely and comfortably at home. The injection uses a small, thin needle and takes only a few seconds.
What is the semaglutide dose escalation schedule?
Semaglutide treatment begins at a low dose of 0.25 mg per week for the first 4 weeks. The dose is gradually increased every 4 weeks through 0.5 mg, 1.0 mg, 1.7 mg, and up to the maintenance dose of 2.4 mg per week. This gradual escalation helps minimize gastrointestinal side effects and allows your body to adjust to the medication.
How is semaglutide different from tirzepatide?
Semaglutide is a GLP-1 receptor agonist, while tirzepatide is a dual GIP/GLP-1 receptor agonist that targets two hormones instead of one. Both are FDA-approved for weight management and administered as weekly injections. Clinical trials have shown slightly greater average weight loss with tirzepatide (up to 22.5%) compared to semaglutide (approximately 15%). Our medical providers can help determine which medication is best suited for your individual needs during your consultation.
Ready to Start Semaglutide?
Schedule a consultation at Femme Aesthetics to find out if semaglutide is right for you. Our medical providers will evaluate your health, discuss your goals, and create a personalized weight loss plan.
In English or Spanish, whichever you’d rather.
Sources
- U.S. Food and Drug Administration. FDA Approves New Medication for Chronic Weight Management.
- U.S. Food and Drug Administration. FDA’s Concerns with Unapproved GLP-1 Drugs Used for Weight Loss.
- Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 2022 (SURMOUNT-1).
